Quick answer
✅ Yes — comfortably. A physician assistant in Knoxville earns roughly $115,209/yr (~$6,754/mo take-home) and a 1BR costs $1,200/mo — that's 18% of take-home on rent. The standard is 30% or less.
TN · 2026
Can a Physician Assistant Afford to Live in Knoxville?
Using local salary estimates and Knoxville's actual cost of living — rent, taxes, utilities, and groceries — here's the real monthly picture for a physician assistant in Knoxville, TN in 2026.
Monthly Budget Breakdown
Gross monthly salary
$115,209/yr local estimate
$9,601
Taxes (federal + state + FICA)
None state income tax
-$2,847
Monthly take-home
After all taxes
$6,754
1BR rent
18% of take-home
-$1,200
Utilities
Electric, gas, internet avg
-$150
Groceries
Single-person estimate
-$365
Transport
Car or transit average
-$350
Left for everything else
Dining, clothing, fun, savings
$4,689
At a 40% savings rate on discretionary income, a physician assistant in Knoxville could save roughly $22,512/year after covering all essentials.
What Does 18% Rent Burden Mean?
The standard rule of thumb is to spend no more than 30% of gross income on rent. At 18% of take-home pay, a physician assistant in Knoxville is well within a healthy range — leaving solid room for savings and discretionary spending.
No state income tax in TN meaningfully helps. A physician assistant earning $115,209/yr saves roughly $5,184/year compared to a 4.5% state income tax state — that's equivalent to one month of rent.
These numbers use a local salary estimate of $115,209/yr — adjusted from the national Physician Assistant median of $126,010/yr based on Knoxville's cost of living index. Actual salaries vary by employer, experience, and specialization.
Best Neighborhoods in Knoxville for a Physician Assistant
Based on walkability, rent levels, and quality of life — not just lowest price.
Downtown
Historic buildings, Market Square (farmers market, restaurants), walkable loft living. 1BR $1,250-$1,500; 2BR $1,500-$1,800.
Old North Knoxville
Gentrifying Victorian homes, locally-owned cafes, young professional vibe. 1BR $1,150-$1,350; 2BR $1,400-$1,650.
Bearden
Upscale suburban, newer homes, shopping, close to UT. 1BR $1,100-$1,300; 2BR $1,350-$1,600.
Frequently Asked Questions
What is the average salary for a Physician Assistant in Knoxville?
A Physician Assistant in Knoxville earns approximately $115,209 per year, based on the national BLS median of $126,010/yr adjusted for Knoxville's cost of living. Actual pay varies by employer, experience, and specialization.
Is Knoxville affordable for a physician assistant in 2026?
Yes. Rent takes around 18% of take-home pay — below the 30% guideline. A physician assistant can live comfortably in Knoxville with room to save.
How much take-home pay does a Physician Assistant get in Knoxville?
After federal taxes, no state income tax, and FICA, a Physician Assistant earning $115,209/yr takes home roughly $6,754/month in Knoxville.
What is the rent-to-income ratio for a Physician Assistant in Knoxville?
A 1-bedroom apartment in Knoxville costs a median of $1,200/month. On a Physician Assistant salary, that's 18% of monthly take-home pay. Financial experts recommend keeping this below 30%.